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1.
J Plast Reconstr Aesthet Surg ; 90: 1-9, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38280337

RESUMO

BACKGROUND: Facial nerve paralysis induced by acute traumatic facial nerve injuries limited to the zygomatic and buccal branches shows unique complications, such as strong co-contractions of the lower facial muscles around the lips during voluntary blinking (ocular-oral synkinesis). We investigated the characteristics of facial complications after facial nerve injury in the mid-face area and reported the treatment results. METHODS: A total of 21 patients with facial nerve injuries to the zygomatic and/or buccal branches were evaluated for the degree of facial synkinesis and mouth asymmetry. Patients with mild-to-moderate symptoms were treated using physical rehabilitation therapy combined with botulinum toxin (Botox) injection, and patients with severe or uncontrolled symptoms were treated using surgical therapy. RESULTS: Initial/final mean synkinesis scores and mouth asymmetry degrees were 2.17/1.75 and 0.85/0.66 in the physical therapy group and 3.11/0.78 and 2.41/-0.31 in the surgery group, respectively. Physical therapy with Botox injection alone did not show significant improvements in synkinetic symptoms of the patients with mild-to-moderate synkinesis (p > 0.05), whereas surgical therapy resulted in significant improvements in synkinesis and mouth asymmetry (p < 0.05). CONCLUSIONS: Surgical treatment is an effective adjustment procedure for the management of facial complications in patients with severe or uncontrolled synkinesis after facial nerve injury to the mid-face area.


Assuntos
Toxinas Botulínicas Tipo A , Traumatismos Faciais , Traumatismos do Nervo Facial , Paralisia Facial , Sincinesia , Humanos , Nervo Facial/cirurgia , Traumatismos do Nervo Facial/complicações , Toxinas Botulínicas Tipo A/uso terapêutico , Sincinesia/tratamento farmacológico , Sincinesia/etiologia , Face , Paralisia Facial/cirurgia , Músculos Faciais/cirurgia
2.
Am J Otolaryngol ; 44(6): 103983, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37531887

RESUMO

OBJECTIVES: To evaluate and compare the long-term results of patients who underwent facial nerve decompression surgery with either transmastoid-supralabyrinthine (TMSL) or combined transmastoid- middle cranial fossa (MCF) approach for traumatic facial nerve paralysis. MATERIALS AND METHODS: This is a single-center retrospective case-control study. The medical records of traumatic facial paralysis patients with House Brackmann (HB) Grade 6 who underwent facial nerve decompression surgery at via either TMSL or MCF approach between January 2011 and December 2017 were reviewed. The patients who had otic capsule involvement and total sensorineural hearing loss, therefore underwent translabyrinthine facial nerve decompression, and the patients follow-up period has not yet reached four years were excluded from the study. Postoperative HB score and hearing status were compared. RESULTS: Eleven patients were operated with MCF approach (group 1), while 9 patients with TMSL approach (group 2). Average age of patients was 20.04 + 15.2 (range:4-47) years. Three (15 %) patients were female, while 17 (85 %) was male. Geniculate ganglion (90 %) was the most affected segment of the facial nerve. Facial nerve edema was observed in all cases, while intraneural hematoma were encountered in 4 (20 %) cases. Statistically significant improvement in median HB scores were reached in both groups, and no significant difference was observed in post-operative HB scores between both techniques. No significant difference in median AC 0,5-4 khZ and BC 0,5-3 kHz thresholds was observed between both techniques. CONCLUSION: Even middle fossa approach is the best surgical technique to explore geniculate ganglion and labyrinthine segment of facial nerve, the functional results of transmastoid supralabrynthine approach, which is not needed craniotomy with low complication rate are as successful as middle fossa approach in selected patients.


Assuntos
Surdez , Traumatismos do Nervo Facial , Paralisia Facial , Humanos , Masculino , Feminino , Pré-Escolar , Criança , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Nervo Facial/cirurgia , Paralisia Facial/etiologia , Paralisia Facial/cirurgia , Estudos Retrospectivos , Fossa Craniana Média/cirurgia , Estudos de Casos e Controles , Traumatismos do Nervo Facial/cirurgia , Traumatismos do Nervo Facial/complicações , Surdez/cirurgia , Descompressão Cirúrgica/métodos
3.
Head Face Med ; 19(1): 31, 2023 Jul 25.
Artigo em Inglês | MEDLINE | ID: mdl-37491262

RESUMO

BACKGROUND: Iatrogenic facial nerve injury is one of the severest complications of middle ear surgery, this study aims to evaluate surgical management and prognosis in the era of improved surgical instruments. METHODS: Patients suffered from facial nerve paralysis after middle ear surgery between January 2000 and December 2019 were retrospectively collected. Demographic characters, primary disease and surgery, details of revision surgery were analyzed. RESULTS: Forty-five patients were collected, of whom 8 were injured at our center and 37 were transferred. For 8 patients injured at our center, seven (87.5%) ranked House-Brackmann (H-B) grade V and one (12.5%) ranked H-B VI before revision surgery; postoperatively, two (25.0%) patients recovered to H-B grade I, four (50.0%) recovered to H-B II, and the other two (25.0%) recovered to H-B III. For 37 patients transferred, thirteen (35.1%) ranked H-B grade V and 24 (64.9%) ranked H-B VI preoperatively, final postoperative grade ranked from H-B grade I to grade V, with H-B I 6 (16.2%) cases, H-B II 6 (16.2%) cases, H-B III 18 (48.6%) cases, H-B IV 5 (13.5%) cases and H-B V 2 (5.4%) cases. The most vulnerable site was tympanic segment (5, 62.5% and 27, 73.0% respectively). Twenty-one (46.7%) patients suffered from mild injury and 24 (53.3%) suffered from partial or complete nerve transection. For surgical management, twenty-one (46.7%) patients received decompression, nineteen (42.2%) received graft and 5 (11.1%) received anastomosis. Those decompressed within 2 months after paralysis had higher possibility of H-B grade I or II recovery (P = 0.026), those received graft within 6 months were more likely to get H-B grade III recovery (P = 0.041), and for patients underwent anastomosis within 6 months, all recovered to H-B grade III. CONCLUSIONS: Tympanic segment is the vulnerable site. If facial nerve paralysis happens, high-resolution computed tomography could help identify the injured site. Timely treatment is important, decompression within 2 months after paralysis, graft and anastomosis within 6 months lead to better recovery.


Assuntos
Paralisia de Bell , Traumatismos do Nervo Facial , Paralisia Facial , Humanos , Traumatismos do Nervo Facial/cirurgia , Traumatismos do Nervo Facial/complicações , Estudos Retrospectivos , Paralisia Facial/etiologia , Paralisia Facial/cirurgia , Prognóstico , Orelha Média/diagnóstico por imagem , Orelha Média/cirurgia , Paralisia de Bell/complicações , Doença Iatrogênica , Nervo Facial/cirurgia , Resultado do Tratamento
4.
J Craniofac Surg ; 34(6): 1841-1844, 2023 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-37427918

RESUMO

Facial nerve trauma occasionally develops during oral and maxillofacial surgery. This study was aimed at enhancing the available knowledge on facial nerve reanimation correlated to surgery and proposing our surgical algorithm. We retrospectively analyzed medical records of patients who underwent facial reanimation surgery at our hospital. The inclusion criterion was surgery for facial reanimation from January 2004 to June 2021. We included 383 eligible patients who underwent facial reanimation surgery. Trauma or maxillofacial neoplasms were noted in 208 of 383 and 164 of 383 cases, respectively. In 238 of 383 cases, nerve branches were likely more vulnerable. Facial nerve anastomosis was performed in 256 patients. Sixty-eight patients received nerve grafts. In 22 patients, distal facial nerve transfer to the masseteric nerve, sublingual nerve, or contralateral facial nerve was performed. Twenty-five patients received static surgery; in most cases, the temporalis fascia flap (20/25) was used. The nerve function outcomes were HB grade I (n=17), Grade Ⅱ (n=108), Grade Ⅲ (n=118), Grade Ⅳ (n=94), and Grade V (n=46). The mean follow-up time was 4.88 ± 3.93 years. Facial paralysis caused by trauma ( P =0.000), branch injury ( P =0.000), and the primary reconstruction of facial nerve ( P =0.000) were predictive of favorable treatment outcomes. Although facial nerve injury caused by trauma was more likely, cases of interference in facial expression could be limited, and so did the injury to branches. Nerve anastomosis was prioritized if a tension-free suture was possible. Maintaining the integrity of the nerve and shortening the duration of mimetic muscular denervation were crucial.


Assuntos
Traumatismos do Nervo Facial , Paralisia Facial , Transferência de Nervo , Procedimentos de Cirurgia Plástica , Humanos , Paralisia Facial/etiologia , Nervo Facial/cirurgia , Estudos Retrospectivos , Traumatismos do Nervo Facial/cirurgia , Traumatismos do Nervo Facial/complicações
5.
Otolaryngol Clin North Am ; 56(3): 567-576, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-36964095

RESUMO

Microsurgical removal of acoustic neuroma has advanced tremendously; however, complications still occur. Facial nerve injury is the most common detrimental complication and should take precedence over gross tumor removal in cases where there is an unfavorable tumor-facial nerve interface. Cerebrospinal fluid leakage can occur even with meticulous closure techniques and is generally treatable with either lumbar-subarachnoid drainage or revision wound closure. Meningitis is a serious complication that requires a high index of suspicion in the postoperative period. Other less common complications include intraoperative and postoperative vascular injuries. Early identification and treatment can prevent devastating outcomes.


Assuntos
Traumatismos do Nervo Facial , Neuroma Acústico , Humanos , Neuroma Acústico/cirurgia , Vazamento de Líquido Cefalorraquidiano/etiologia , Vazamento de Líquido Cefalorraquidiano/terapia , Nervo Facial , Traumatismos do Nervo Facial/complicações , Complicações Pós-Operatórias/etiologia , Estudos Retrospectivos
6.
J Laryngol Otol ; 137(12): 1334-1339, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-36382446

RESUMO

OBJECTIVE: The current study evaluated the effectiveness of endoscopic transcanal facial nerve decompression in patients with post-traumatic facial nerve paralysis. METHODS: This retrospective study included 10 patients with post-traumatic complete facial nerve paralysis who underwent endoscopic transcanal facial nerve decompression. The surgical technique was explained step by step, and the surgical complications, hearing status and facial nerve function 12 months post-operatively were reported. RESULTS: Endoscopic transcanal facial nerve decompression allowed exposure of the geniculate ganglion to the mastoid segment. The facial nerve function improved from House-Brackmann grade VI to grades I and II in 8 of 10 (80 per cent) patients, and 2 patients experienced partial recovery (House-Brackmann grades III and IV). No severe complication was reported. CONCLUSION: Endoscopic transcanal facial nerve decompression, involving the nerve from the geniculate ganglion to the mastoid segment, is a safe and effective approach in patients with post-traumatic facial nerve paralysis.


Assuntos
Traumatismos do Nervo Facial , Paralisia Facial , Humanos , Nervo Facial/cirurgia , Gânglio Geniculado/cirurgia , Processo Mastoide/cirurgia , Estudos Retrospectivos , Traumatismos do Nervo Facial/cirurgia , Traumatismos do Nervo Facial/complicações , Paralisia/complicações , Paralisia/cirurgia , Paralisia Facial/etiologia , Paralisia Facial/cirurgia , Descompressão Cirúrgica/efeitos adversos , Descompressão Cirúrgica/métodos
7.
J Clin Monit Comput ; 37(2): 575-583, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-36333576

RESUMO

PURPOSE: Facial nerve damage in vestibular schwannoma surgery is associated with A-train patterns in free-running EMG, correlating with the degree of postoperative facial palsy. However, anatomy, preoperative functional status, tumor size and occurrence of A-trains clusters, i.e., sudden A-trains in most channels may further contribute. In the presented study, we examine neural networks to estimate postoperative facial function based on such features. METHODS: Data from 200 consecutive patients were used to train neural feed-forward networks (NN). Estimated and clinical postoperative House and Brackmann (HB) grades were compared. Different input sets were evaluated. RESULTS: Networks based on traintime, preoperative HB grade and tumor size achieved good estimation of postoperative HB grades (chi2 = 54.8), compared to using tumor size or mean traintime alone (chi2 = 30.6 and 31.9). Separate intermediate nerve or detection of A-train clusters did not improve performance. Removal of A-train cluster traintime improved results (chi2 = 54.8 vs. 51.3) in patients without separate intermediate nerve. CONCLUSION: NN based on preoperative HB, traintime and tumor size provide good estimations of postoperative HB. The method is amenable to real-time implementation and supports integration of information from different sources. NN could enable multimodal facial nerve monitoring and improve postoperative outcomes.


Assuntos
Traumatismos do Nervo Facial , Paralisia Facial , Neuroma Acústico , Humanos , Paralisia Facial/complicações , Neuroma Acústico/cirurgia , Nervo Facial/cirurgia , Traumatismos do Nervo Facial/complicações , Traumatismos do Nervo Facial/diagnóstico , Redes Neurais de Computação , Complicações Pós-Operatórias/diagnóstico , Estudos Retrospectivos
8.
J Burn Care Res ; 43(4): 981-983, 2022 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-35452501

RESUMO

Fireworks injuries can result in devastating cutaneous burns and may be further complicated in the head and neck region by the presence of specialized deeper structures. In the United States, the head and neck remain the most commonly injured sites, with the majority of these injuries constituting burns. We present an adult patient who suffered an accidental right cheek burn injury and went on to experience a complex pattern of findings including pneumomediastinum, facial nerve palsy, and sialocele formation.


Assuntos
Traumatismos por Explosões , Queimaduras , Traumatismos Faciais , Traumatismos do Nervo Facial , Enfisema Mediastínico , Adulto , Traumatismos por Explosões/complicações , Queimaduras/complicações , Bochecha , Traumatismos Faciais/complicações , Traumatismos Faciais/cirurgia , Traumatismos do Nervo Facial/complicações , Humanos , Enfisema Mediastínico/complicações , Estados Unidos
9.
J Craniofac Surg ; 33(5): e532-e537, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35275857

RESUMO

PURPOSE: Surgical treatment for condylar fractures is a challenging procedure most debated in scientific literature without a broad consensus on the selection of surgical techniques to be used and relative indications.The goal of this work is to propose a multistep surgical planning for condylar fractures based on an effective mini-invasive approach and safe procedure aimed to avoid as much as possible skin incision in the aesthetic areas of the face and neck, to decrease the risk of facial nerve injury. METHODS: Ten patients with dislocated condylar neck fractures and sub-condylar fractures were included in this study.All the patients were studied with radiological images, computed tomography scans with three-dimensional reconstructions preoperatively and immediate postoperatively.Patients were evaluated pre- and post-operatively for dental occlusion, bone fragment alignment after reduction and after fixation, facial nerve functionality, skin scarring, temporomandibular joint functionality, temporomandibular joint symptomatology, and patient satisfaction. RESULTS: Results were satisfactory for different parameters evaluated. No significant complications resulted in follow-up, particularly for facial nerve injury. By using this multistep procedure with each stage functional to the following one, the authors achieved satisfactory results following treatment of dislocated condylar fractures.


Assuntos
Traumatismos do Nervo Facial , Luxações Articulares , Côndilo Mandibular , Fraturas Mandibulares , Estética Dentária , Traumatismos do Nervo Facial/complicações , Fixação Interna de Fraturas/métodos , Humanos , Luxações Articulares/complicações , Côndilo Mandibular/diagnóstico por imagem , Côndilo Mandibular/lesões , Côndilo Mandibular/cirurgia , Fraturas Mandibulares/complicações , Fraturas Mandibulares/diagnóstico por imagem , Fraturas Mandibulares/cirurgia , Resultado do Tratamento
10.
Ann Otol Rhinol Laryngol ; 131(4): 365-372, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34096343

RESUMO

OBJECTIVES: Facial paralysis is a debilitating condition with substantial functional and psychological consequences. This feline-model study evaluates whether facial muscles can be selectively activated in acute and chronic implantation of 16-channel multichannel cuff electrodes (MCE). METHODS: Two cats underwent acute terminal MCE implantation experiments, 2 underwent chronic MCE implantation in uninjured facial nerves (FN) and tested for 6 months, and 2 underwent chronic MCE implantation experiments after FN transection injury and tested for 3 months. The MCE were wrapped around the main trunk of the skeletonized FN, and data collection consisted of EMG thresholds, amplitudes, and selectivity of muscle activation. RESULTS: In acute experimentation, activation of specific channels (ie, channels 1-3 and 6-8) resulted in selective activation of orbicularis oculi, whereas activation of other channels (ie, channels 4, 5, or 8) led to selective activation of levator auris longus with higher EMG amplitudes. MCE implantation yielded stable and selective facial muscle activation EMG thresholds and amplitudes up to a 5-month period. Modest selective muscle activation was furthermore obtained after a complete transection-reapproximating nerve injury after a 3-month recovery period and implantation reoperation. Chronic implantation of MCE did not lead to fibrosis on histology. Field steering was achieved to activate distinct facial muscles by sending simultaneous subthreshold currents to multiple channels, thus theoretically protecting against nerve damage from chronic electrical stimulation. CONCLUSION: Our proof-of-concept results show the ability of an MCE, supplemented with field steering, to provide a degree of selective facial muscle stimulation in a feline model, even following nerve regeneration after FN injury. LEVEL OF EVIDENCE: N/A.


Assuntos
Terapia por Estimulação Elétrica/instrumentação , Eletrodos Implantados , Músculos Faciais/inervação , Músculos Faciais/fisiopatologia , Traumatismos do Nervo Facial/complicações , Paralisia Facial/terapia , Contração Muscular/fisiologia , Animais , Gatos , Modelos Animais de Doenças , Eletromiografia , Traumatismos do Nervo Facial/fisiopatologia , Paralisia Facial/etiologia , Paralisia Facial/fisiopatologia , Feminino
11.
J Craniofac Surg ; 33(3): 750-753, 2022 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-34334751

RESUMO

INTRODUCTION: In the etiology of facial nerve palsy, trauma is the most important. Our aim was to present our experience gained by evaluating the surgical approaches we have used in extratemporal and intratemporal facial nerve injuries and their long-term results, also to contribute to the consensus that will be formed on this subject. MATERIALS AND METHODS: Thirteen patients among 24 patients who underwent surgery with a diagnosis of traumatic facial paralysis were evaluated in this study. The clinical response of these patients to treatment was examined by classifying them according to the House-Brackmann classification in the preoperative and postoperative periods. RESULTS: Of the 13 patients, 9 had fractures due to temporal bone trauma, and 4 had nerve damage in the extratemporal part of the facial nerve. in the treatment, facial nerve decompression was performed using the middle fossa approach in 9 patients with temporal bone fractures. in the 4 patients with extratemporal facial nerve injury, graft repair or primary suturing was performed. in the postoperative period, the stages of the patients were III or below in 12 patients (92%), and only 1 (8%) patient remained in stage IV. DISCUSSION: When the postop conditions of the patients were examined according to House-Brackmann staging, it was observed that surgical treatment caused a significant improvement in the functions of the facial nerve. CONCLUSIONS: Our results showed that surgery was an effective treatment method in patients with indications for traumatic facial paralysis.


Assuntos
Traumatismos do Nervo Facial , Paralisia Facial , Descompressão Cirúrgica/métodos , Nervo Facial/cirurgia , Traumatismos do Nervo Facial/complicações , Traumatismos do Nervo Facial/cirurgia , Paralisia Facial/diagnóstico , Paralisia Facial/etiologia , Paralisia Facial/cirurgia , Humanos , Estudos Retrospectivos , Osso Temporal/lesões , Osso Temporal/cirurgia , Resultado do Tratamento
12.
Laryngoscope ; 132(6): 1295-1299, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-34636425

RESUMO

OBJECTIVES/HYPOTHESIS: Mandibular distraction osteogenesis (MDO) is a safe and effective surgery to address respiratory and feeding issues due to micrognathia in patients with Robin Sequence (RS). Previous studies examining postoperative complications in neonates receiving MDO have considered 4 kg as the cut-off for low weight; however, an increasing number of MDO interventions are performed in infants <4 kg. To determine if a weight <3 kg at time of MDO is a risk factor for postoperative complications or need for subsequent tracheostomy or gastrostomy tube (G-tube). STUDY DESIGN: Retrospective chart review. METHODS: A retrospective review of all infants <6 months of age undergoing MDO at two tertiary pediatric hospitals from 2008 to 2018. Demographic data, syndromic status, weight, and age at time of surgery, length of postoperative hospital stay, and postoperative outcomes were recorded including tracheostomy placement, G-tube placement, hardware infection, reintubation, facial/marginal mandibular nerve damage, and need for revision MDO. RESULTS: Sixty-nine patients with RS were included. The mean age at MDO was 25 ± 20 days and mean weight was 3.32 ± 0.44 kg. There was no statistically significant correlation between weight (P = .699) or age (P = .422) and unfavorable postoperative outcomes. No patients (0%) underwent tracheostomy pre-MDO. Two patients (2.9%) required tracheostomy postsurgery; neither was <3 kg. Eight patients (11.6%) required a G-tube postoperatively. CONCLUSION: Newborns <3 kg who undergo MDO experience the same rates of success and complication as larger infants, suggesting that MDO is a safe and efficacious procedure in infants less than 3 kg. Laryngoscope, 132:1295-1299, 2022.


Assuntos
Obstrução das Vias Respiratórias , Traumatismos do Nervo Facial , Osteogênese por Distração , Síndrome de Pierre Robin , Obstrução das Vias Respiratórias/etiologia , Criança , Traumatismos do Nervo Facial/complicações , Humanos , Lactente , Recém-Nascido , Mandíbula/cirurgia , Osteogênese por Distração/efeitos adversos , Osteogênese por Distração/métodos , Síndrome de Pierre Robin/complicações , Síndrome de Pierre Robin/cirurgia , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Estudos Retrospectivos , Resultado do Tratamento
13.
BMC Surg ; 21(1): 32, 2021 Jan 08.
Artigo em Inglês | MEDLINE | ID: mdl-33419427

RESUMO

BACKGROUND: Early surgical repair to restore nerve integrity has become the most commonly practiced method for managing facial nerve injury. However, the evidence for the efficacy of surgical repair for restoring the function of facial nerves remains deficient. This study evaluated the outcomes of surgical repair for facial nerve lesions. METHODS: This retrospective observational study recruited 28 patients with the diagnosis of facial nerve injury who consecutively underwent surgical repairs from September 2012 to May 2019. All related clinical data were retrospectively analyzed according to age, sex, location of the facial nerve lesion, size of the facial nerve defect, method of repair, facial electromyogram, and blink reflex. Facial function was then stratified with the House-Brackmann grading system pre-operation and 3, 9, 15, and 21 months after surgical repair. RESULTS: The 28 patients enrolled in this study included 17 male and 11 female patients with an average age of 34.3 ± 17.4 years. Three methods were applied for the repair of an injured facial nerve, including great auricular nerve transplantation in 15 patients, sural nerve grafting in 7 patients, and hypoglossal to facial nerve anastomosis in 6 patients. Facial nerve function was significantly improved at 21 months after surgery compared with pre-operative function (P = 0.008). Following surgical repair, a correlation was found between the amplitude of motor unit potential (MUP) and facial nerve function (r = -6.078, P = 0.02). Moreover, the extent of functional restoration of the facial nerve at 21 months after surgery depended on the location of the facial nerve lesion; lesions at either the horizontal or vertical segment showed significant improvement(P = 0.008 and 0.005), while no functional restoration was found for lesions at the labyrinthine segment (P = 0.26). CONCLUSIONS: For surgical repair of facial nerve lesions, the sural nerve, great auricular nerve, and hypoglossal-facial nerve can be grafted effectively to store the function of a facial nerve, and MUP may provide an effective indicator for monitoring the recovery of the injured nerve.


Assuntos
Traumatismos do Nervo Facial/cirurgia , Nervo Facial , Paralisia Facial , Adolescente , Adulto , Anastomose Cirúrgica , Plexo Cervical/cirurgia , Nervo Facial/cirurgia , Traumatismos do Nervo Facial/complicações , Paralisia Facial/etiologia , Paralisia Facial/cirurgia , Feminino , Humanos , Nervo Hipoglosso/transplante , Masculino , Pessoa de Meia-Idade , Recuperação de Função Fisiológica , Estudos Retrospectivos , Nervo Sural/transplante , Resultado do Tratamento , Adulto Jovem
14.
Laryngoscope ; 131(1): 17-24, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-32096879

RESUMO

OBJECTIVE: Dysphagia is common following facial nerve injury; however, research is sparse regarding swallowing-related outcomes and targeted treatments. Previous animal studies have used eye blink and vibrissae movement as measures of facial nerve impairment and recovery. The purpose of this study was to create a mouse model of facial nerve injury that results in dysphagia to enhance translational research outcomes. STUDY DESIGN: Prospective animal study. METHODS: Twenty C57BL/6J mice underwent surgical transection of the main trunk (MT) (n = 10) or marginal mandibular branch (MMB) (n = 10) of the left facial nerve. Videofluoroscopic swallow study (VFSS) assays for drinking and eating were performed at baseline and 14 days postsurgery to quantify several deglutition-related outcome measures. RESULTS: VFSS analysis revealed that MT transection resulted in significantly slower lick and swallow rates during drinking (P ≤ .05) and significantly slower swallow rates and longer inter-swallow intervals during eating (P ≤ .05), congruent with oral and pharyngeal dysphagia. After MMB transection, these same VFSS metrics were not statistically significant (P > .05). CONCLUSION: The main finding of this study was that transection of the facial nerve MT leads to oral and pharyngeal stage dysphagia in mice; MMB transection does not. These results from mice provide novel insight into specific VFSS metrics that may be used to characterize dysphagia in humans following facial nerve injury. We are currently using this surgical mouse model to explore promising treatment modalities such as electrical stimulation to hasten recovery and improve outcomes following various iatrogenic and idiopathic conditions affecting the facial nerve. LEVEL OF EVIDENCE: NA Laryngoscope, 131:17-24, 2021.


Assuntos
Transtornos de Deglutição/etiologia , Traumatismos do Nervo Facial/complicações , Animais , Modelos Animais de Doenças , Fluoroscopia , Camundongos , Camundongos Endogâmicos C57BL , Estudos Prospectivos , Gravação em Vídeo
15.
J Plast Reconstr Aesthet Surg ; 74(1): 160-167, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-32631719

RESUMO

Early cases of facial nerve injury are best treated by restoring the neural pathway to the same existing facial muscles. Knowledge of the exact territory of facial nerve injury is required to design a plane for the reconstruction of these injuries and to compare results. The current study aims to design a classification system for territories of facial nerve injury based on the location of nearest healthy fascicles to the site of injury both proximally and distally. Two hundred-one patients with early facial nerve injury were assessed for treatment. According to the results of the exploration, 13 territories of injury were identified. The management strategy was planned according to the territory of injury. The current classification system is a simple, easy and effective method for the classification of territories of facial nerve injury. The classification system accurately describes the nearest possible healthy proximal and distal fascicles and can be employed to easily report cases and implement a management plan. This classification scheme also allows us to more effectively compare results.


Assuntos
Traumatismos do Nervo Facial/classificação , Traumatismos do Nervo Facial/cirurgia , Adolescente , Adulto , Criança , Pré-Escolar , Músculos Faciais/inervação , Nervo Facial/cirurgia , Traumatismos do Nervo Facial/complicações , Paralisia Facial/etiologia , Paralisia Facial/cirurgia , Feminino , Humanos , Nervo Hipoglosso/transplante , Lactente , Masculino , Nervo Mandibular/transplante , Pessoa de Meia-Idade , Procedimentos Neurocirúrgicos , Adulto Jovem
16.
Acta Otolaryngol ; 141(3): 222-225, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33151110

RESUMO

BACKGROUND: As tympanotomy using the transcanal approach was a routine surgical technique for traumatic ossicular disruption, the efficacy of the posterior tympanum approach was rarely explored. AIM: This study aimed to investigate whether the hearing outcomes improved after simultaneous ossiculoplasty and facial nerve decompression using the posterior tympanum approach compared with the transcanal approach. MATERIAL AND METHODS: The data of 11 patients who underwent ossiculoplasty and facial nerve decompression using the posterior tympanum approach and 21 patients who underwent ossiculoplasty via transcannal approach were analyzed. RESULTS: The average air-bone gap (ABG) of patients undergoing posterior tympanotomy showed a statistically significant improvement. Postoperative ABG within 20 dB was observed in 81.8% of patients in the posterior tympanum group and 76.2% of patients in the transcanal group. However, the ABG closure in the two groups was not statistically different. CONCLUSIONS AND SIGNIFICANCE: Simultaneous ossiculoplasty using the posterior tympanum approach was practical, and the hearing outcomes were promising for the patients with traumatic facial nerve paralysis and ossicular disruption.


Assuntos
Ossículos da Orelha/lesões , Traumatismos do Nervo Facial/cirurgia , Paralisia Facial/cirurgia , Audição , Procedimentos Cirúrgicos Otológicos/métodos , Membrana Timpânica/cirurgia , Adulto , Audiometria de Tons Puros , Limiar Auditivo , Condução Óssea , Traumatismos Craniocerebrais/complicações , Ossículos da Orelha/cirurgia , Traumatismos do Nervo Facial/complicações , Paralisia Facial/etiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prótese Ossicular , Substituição Ossicular , Adulto Jovem
17.
Plast Reconstr Surg ; 146(6): 1295-1305, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-33234960

RESUMO

BACKGROUND: Posttraumatic facial paralysis is a disabling condition. Current surgical management by faciofacial nerve suture provides limited recovery. To improve the outcome, the authors evaluated an add-on strategy based on a syngeneic transplantation of nasal olfactory stem cells in a rat model of facial nerve injury. The main readouts of the study were the recording of whisking function and buccal synkinesis. METHODS: Sixty rats were allocated to three groups. Animals with a 2-mm facial nerve loss were repaired with a femoral vein, filled or not with olfactory stem cells. These two groups were compared to similarly injured rats but with a faciofacial nerve suture. Olfactory stem cells were purified from rat olfactory mucosa. Three months after surgery, facial motor performance was evaluated using video-based motion analysis and electromyography. Synkinesis was assessed by electromyography, using measure of buccal involuntary movements during blink reflex, and double retrograde labeling of regenerating motoneurons. RESULTS: The authors' study reveals that olfactory stem cell transplantation induces functional recovery in comparison to nontransplanted and faciofacial nerve suture groups. They significantly increase (1) maximal amplitude of vibrissae protraction and retraction cycles and (2) angular velocity during protraction of vibrissae. They also reduce buccal synkinesis, according to the two techniques used. However, olfactory stem cell transplantation did not improve axonal regrowth of the facial nerve, 3 months after surgery. CONCLUSIONS: The authors show here that the adjuvant strategy of syngeneic transplantation of olfactory stem cells improves functional recovery. These promising results open the way for a phase I clinical trial based on the autologous engraftment of olfactory stem cells in patients with a facial nerve paralysis.


Assuntos
Traumatismos do Nervo Facial/cirurgia , Paralisia Facial/cirurgia , Transplante de Células-Tronco/métodos , Sincinesia/cirurgia , Enxerto Vascular/métodos , Animais , Técnicas de Observação do Comportamento , Modelos Animais de Doenças , Eletromiografia , Nervo Facial/fisiopatologia , Nervo Facial/cirurgia , Traumatismos do Nervo Facial/complicações , Traumatismos do Nervo Facial/fisiopatologia , Paralisia Facial/diagnóstico , Paralisia Facial/etiologia , Paralisia Facial/fisiopatologia , Feminino , Veia Femoral/transplante , Humanos , Regeneração Nervosa/fisiologia , Mucosa Olfatória/citologia , Ratos , Recuperação de Função Fisiológica , Sincinesia/diagnóstico , Sincinesia/etiologia , Sincinesia/fisiopatologia , Transplante Isogênico/métodos , Vibrissas/inervação , Vibrissas/fisiologia , Gravação em Vídeo
18.
Clin Neurol Neurosurg ; 194: 105819, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-32259672

RESUMO

OBJECTIVE: Facial pain refractory to medical treatments may benefit from neurosurgical interventions. Only a few studies have reported on the efficacy of peripheral trigeminal stimulation and more specifically supraorbital nerve (SON) and infraorbital nerve (ION) stimulation for the treatment of facial pain. PATIENTS AND METHODS: In the present study, we identified all patients at our institution who underwent SON and/or ION stimulation for treatment of facial pain due to post-herpetic, traumatic or idiopathic etiology. Relevant pre and post-operative outcomes were analyzed. RESULTS: We identified 15 patients who underwent SON and/or ION stimulation. Among them, 12 (80 %) endorsed >50 % pain relief during the trial stimulation period. After a median follow-up of 5.8 months with permanent implantation, 1 patient (8.3 %) was diagnosed with lead erosion and IPG migration, two patients had lead infections (16.7 %) and one (8.3 %) had wound dehiscence. No lead migrations were identified during the long-term follow-up. The VAS score showed a statistically significant reduction from a median pre-operative score of 7 to a post-operative score of 1.8 (p = 0.011), which corresponded to a 74.3 % average pain reduction. CONCLUSION: SON and/or ION stimulation can be an effective treatment for intractable facial pain due to post-herpetic, traumatic or idiopathic etiology; however the complication rate is relatively high. Future prospective studies with longer follow-up periods are warranted.


Assuntos
Terapia por Estimulação Elétrica/métodos , Dor Facial/cirurgia , Dor Facial/terapia , Nervo Trigêmeo , Adulto , Idoso , Idoso de 80 Anos ou mais , Terapia por Estimulação Elétrica/efeitos adversos , Eletrodos Implantados/efeitos adversos , Traumatismos do Nervo Facial/complicações , Traumatismos do Nervo Facial/terapia , Feminino , Seguimentos , Migração de Corpo Estranho/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Neuralgia Pós-Herpética/terapia , Procedimentos Neurocirúrgicos/métodos , Medição da Dor , Dor Intratável , Nervos Periféricos , Complicações Pós-Operatórias/epidemiologia , Estudos Retrospectivos , Resultado do Tratamento
20.
Ann Otol Rhinol Laryngol ; 129(5): 505-511, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-31888352

RESUMO

OBJECTIVES: Immediate facial nerve substitution or graft technique has been used for the repair of facial nerve defects occurring as a result of tumour dissection. However, some patients report unsatisfactory outcomes, such as difficulty in maintaining resting or smiling symmetry, due to persistent flaccid facial palsy. Here we evaluated the functional outcomes of transferring the masseteric branch of the trigeminal nerve to the facial nerve adjunct to facial nerve graft. METHODS: We reviewed the medical records of seven patients who underwent facial reanimation surgery between 2014 and 2016. The patients were divided into two groups according to the type of facial reanimation surgery: group A, masseteric nerve innervation with interposition graft; group B, interposition graft only. The postoperative resting symmetry and dynamic movement were compared. RESULTS: Facial contraction was first observed in group A at 4 months and in group B at 7.3 months. Most of the patients achieved reliable resting symmetry; however, one patient in group B exhibited unsatisfactory facial weakness on the affected side. Group A patients showed better dynamic movement than group B patients. Eye closure, oral excursion and oral continence were better in group A than in group B patients. Smile symmetry in both groups was similar due to hyperkinetic movement in group A patients and flaccidity in group B patients. CONCLUSIONS: Dual innervation of the masseteric branch of the trigeminal nerve improves the dynamic movement of paralysed facial muscles and shortens the recovery period in patients with iatrogenic facial palsy.


Assuntos
Traumatismos do Nervo Facial/cirurgia , Nervo Facial/cirurgia , Paralisia Facial/cirurgia , Nervo Mandibular/transplante , Músculo Masseter/inervação , Transferência de Nervo/métodos , Adolescente , Adulto , Idoso , Expressão Facial , Nervo Facial/fisiopatologia , Traumatismos do Nervo Facial/complicações , Traumatismos do Nervo Facial/fisiopatologia , Paralisia Facial/etiologia , Paralisia Facial/fisiopatologia , Feminino , Seguimentos , Humanos , Doença Iatrogênica , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Adulto Jovem
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